Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation
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چکیده
منابع مشابه
Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation.
BACKGROUND PCNA (proliferating cell nuclear antigen) has been found in the nuclei of yeast, plant and animal cells that undergo cell division, suggesting a function in cell cycle regulation and/or DNA replication. It subsequently became clear that PCNA also played a role in other processes involving the cell genome. SCOPE This review discusses eukaryotic PCNA, with an emphasis on plant PCNA, ...
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Mismatch Repair (MMR) is closely linked to DNA replication; however, other than the role of the replicative sliding clamp (PCNA) in various MMR functions, the linkage between DNA replication and MMR has been difficult to investigate. Here we use an in vitro DNA replication system based on simian virus 40, to investigate MMR recruitment to replicating DNA. Both DNA replication and MMR proteins a...
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ژورنال
عنوان ژورنال: Annals of Botany
سال: 2010
ISSN: 1095-8290,0305-7364
DOI: 10.1093/aob/mcq243